Acne

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Therapeutics is one of the most significant challenges in pediatric dermatology. Children have been identified as “therapeutic orphans”, with few options that have FDA-approved pediatric indications. Access to new and novel treatments like biologics is especially limited. Supportive legislation, beginning with the Best Pharmaceuticals for Children Act (bpca.nichd.nih.gov), has marked the dawn of a new era.

Though it’s known that oral contraceptive pills (OCPs) and systemic antibiotics are both effective in managing acne, there’s been precious little research comparing the two therapies head-to-head - until now.

Perceived beauty goes beyond numeric values and divine proportions. In fact, beauty in the beholder’s eyes is a collage of geographic, ethnic and demographic influences, according to research published in the March issue of Journal of Craniofacial Surgery.

Biofilms are increasingly implicated as the reason why currently available acne treatments sometimes prove ineffective in acne vulgaris patients, begging the need for more effective targeted therapies directed against biofilm formation.

Gluten and gluten-sensitive enteropathy have become hot topics among the lay public and in medical practices. John Zone, M.D., from the University of Utah, Salt Lake City, discusses how gluten sensitive enteropathy may impact many areas of dermatology.

I thoroughly enjoyed the lead article about “antimicrobial stewardship” in the October edition of Dermatology Times (“Antimicrobial stewardship: How dermatologists can be part of the solution, Vol. 34, No. 10). It succinctly and effectively detailed that for healthcare providers in general and dermatologists in specific, it is our duty to utilize antimicrobials appropriately.

New drugs, data and guidelines on acne and rosacea treatment were among the takeaways from days two and three of MauiDerm 2014. Presenters also described evidence-based suggestions for managing pigmentary disorders and updated information on infectious diseases.

Most patients that complain of acne within 48 hours of applying sunscreen probably are not experiencing true acne with follicular rupture, but rather irritant follicular contact dermatitis or possibly miliaria rubra and miliaria pustulosa. It may be worthwhile to suggest patients try a spray formulation.

Although the symptoms of acne and rosacea are well established, clear and definitive etiologies of these conditions have largely been unknown. Recent research, however, has shed new light into the pathophysiology of these conditions, paving the way for more targeted therapies.

Dermatologists generally know that the sensitivity of many pathogens to the antibiotics used to treat them is decreasing, experts say. But many dermatologists may not appreciate their specialty’s role in potentially fueling the problem.