July 31st 2025
O'Dowd discusses J&J's recent NDA submission for icotrokinra in psoriasis.
July 22nd 2025
Sun Pharma reveals promising phase 3 results for tildrakizumab (Ilumya) in treating PsA, showing significant symptom improvement in patients.
Matthew Zirwas, MD, discusses the complexities of safety analysis in psoriasis clinical trials, advocating for exposure-adjusted incidence rates to enhance risk communication.
July 21st 2025
Johnson & Johnson submitted an NDA for icotrokinra, a promising new treatment for moderate to severe plaque psoriasis in adults and adolescents.
A retrospective case series found that apremilast induced complete remission in 6 men with treatment-resistant genital psoriasis.
Tailoring Biologic Options in Medicare-Aged Patients With Plaque Psoriasis
At a recent Dermatology Times Case-Based Roundtable event, David Cotter, MD, PhD, reviewed treatment considerations for older patients with moderate to severe PsO who are candidates for biologic therapy.
Boehringer Ingleheim, LEO Pharma Announce Partnership to Advance Spesolimab in GPP and Beyond
The pharmaceutical companies announced an exclusive global license and transfer agreement for the advancement and commercialization of Spevigo.
Data Show Spesolimab Maintains Skin Clarity Between GPP Flares
Spesolimab effectively targets the IL-36 receptor, reducing inflammation and preventing flares in generalized pustular psoriasis, offering new hope for patients.
Beyond the Label: Evaluating Bimekizumab’s Mental Health Profile in Psoriasis Treatment
Although bimekizumab carries a precaution for suicidal ideation and behavior, current data suggest it may improve mental health outcomes for patients with psoriasis.
VYNE Unblinds Early VYN202 Data After Safety Pause
VYNE Therapeutics updates on VYN202, revealing promising early results in psoriasis treatment despite a clinical hold due to safety concerns.
Seven-Year Safety Review Confirms Brodalumab’s Steady Risk Profile in US Postmarketing Surveillance
A poster from SDPA 2025 showed brodalumab maintains a consistent safety profile with no completed suicides and low infection rates.
Long-Term Control of Generalized Pustular Psoriasis Achieved With Subcutaneous Spesolimab Following Severe Flare
Subcutaneous spesolimab maintained durable GPP control for 12 months after rapid clearance from IV spesolimab in a high-risk elderly patient.
New Consensus Defines Remission in Plaque Psoriasis to Standardize Care
Remission is now defined as 0% BSA or IGA 0 for ≥6 months on treatment, per a Delphi consensus led by the National Psoriasis Foundation.
Inside IL-17 Inhibitors Advancing Psoriasis Care
Explore the latest insights on IL-17 inhibitors for psoriasis, highlighting their mechanisms, real-world benefits, and future treatment strategies.
Data Show Up to 5-Fold Higher Mortality Risk in Patients With Generalized Pustular Psoriasis
New research reveals that early discontinuation of adjuvant immunotherapy for melanoma does not lead to worse outcomes.
Diagnosing and Managing GPP: Top Insights From the Experts
Aaron Farberg, MD, led a panel exploring the challenges of diagnosing and treating generalized pustular psoriasis and the promise of targeted therapies.
Targeted TYK2 Blockade for PsO Without JAK1/2/3 Impact
Zasocitinib emerges as a promising oral therapy for psoriasis and psoriatic arthritis, showcasing superior selectivity and safety compared to traditional JAK inhibitors.
Arcutis’ Roflumilast Becomes First FDA-Approved Treatment to Receive the NPF’s Seal of Recognition
The National Psoriasis Foundation Seal of Recognition program has expanded to prescription drugs, making roflumilast the first to achieve the indication.
Dermatology Times Spot Test: May 24, 2025
Put your dermatology expertise to the test with Dermatology Times’ interactive quiz series!
ICYMI: FDA Grants Adalimumab-aaty Interchangeability Designation
Celltrion's Yuflyma gains full FDA interchangeability, enhancing patient access and affordability for various inflammatory conditions.
FDA Approves Arcutis’ Roflumilast Foam for Plaque Psoriasis
FDA approves Arcutis' roflumilast foam, a groundbreaking treatment for plaque psoriasis, offering a steroid-free, effective solution for patients aged 12 and older.
Real-World Data on the Adverse Effects of Apremilast and Deucravacitinib for Psoriasis
A recent analysis reveals safety profiles of apremilast and deucravacitinib for psoriasis, highlighting unique adverse events and long-term monitoring needs.
Ascletis Receives FDA Clearance to Advance ASC50, a Novel Oral IL-17 Inhibitor, Into Phase 1 Psoriasis Trial
Ascletis Pharma's investigational new drug application for ASC50 gains FDA clearance for a phase 1 trial for mild to moderate psoriasis.
AC-201 Shows Strong Phase 2 Results in Psoriasis Trial
Accropeutics reveals promising Phase 2 trial results for AC-201, a selective TYK2/JAK1 inhibitor, showing significant efficacy in treating plaque psoriasis.
Psoriasis Linked to Sleep Disorders in Diverse Adults
Psoriasis significantly impacts sleep health, with diverse populations facing increased risks of sleep disorders, highlighting urgent clinical needs for tailored interventions.
Psoriasis and Cellulitis Burden Has Increased in the US, According to New Posters
Recent posters at SID revealed significant increases in psoriasis and cellulitis cases in the US, highlighting urgent needs for prevention and treatment strategies.
GLP-1 Therapy Offers Dual Benefits for Skin and Heart
GLP-1 receptor agonists show promise in reducing cardiovascular risks for patients with chronic inflammatory skin diseases like psoriasis and atopic dermatitis.
New Guidance Aims to Improve Genital Psoriasis Treatment
New guidelines from the Genital Psoriasis Wellness Consortium highlight the significant impact of genital psoriasis on patients, emphasizing improved diagnosis and personalized treatment.
IL-23 and IL-17 Inhibitors Reduce Cardiovascular Outcomes in Statin-Treated Psoriasis Patients
Biologics significantly lower cardiovascular risks in psoriasis patients on statins, highlighting their dual benefits for skin and heart health.
Risankizumab Effective in Difficult-to-Treat Psoriasis Areas
Discover the promising results of risankizumab for treating genital and scalp psoriasis, showcasing significant improvements in symptoms and quality of life.
Tyk2 Inhibition Prevents Islet Inflammation and Delays Type 1 Diabetes Development in Mice
New research reveals a promising strategy to slow type 1 diabetes progression by targeting inflammation with an existing psoriasis drug.
New-Onset Psoriasis After Abrocitinib Treatment for Atopic Dermatitis
Abrocitinib’s targeted inhibition of JAK1 offers effective control of AD, but may, in rare instances, lead to a shift in immune expression resulting in paradoxical psoriasis.
Icotrokinra Effective in High-Impact Psoriasis Areas
Johnson & Johnson's icotrokinra shows promising results in treating moderate plaque psoriasis, especially in challenging areas like the scalp and genitals.
Artax Presents Phase 2a Results of AX-158 for Plaque Psoriasis
The promising safety and efficacy results were presented at the Society for Investigative Dermatology 2025 Annual Meeting.
Exploring the Role of GLP-1 Receptor Agonists in Psoriasis
Explore the potential of GLP-1 receptor agonists in psoriasis management, highlighting their immunomodulatory effects and metabolic benefits for patients.