Psoriasis

The realization of the critical importance of the IL-17 and 23 pathways have led to the development of numerous therapies that target parts of the immune system.

Researchers in Taiwan investigated whether behavioral modifications such as weight reduction, alcohol abstinence, smoking cessation and exercise could impact psoriasis severity. Read what they discovered in this article.

Researchers employed the the Citizen Pscientist, an online patient portal developed by the National Psoriasis Foundation, to investigate chronic sleep dysfunction prevalence in psoriasis. Read what they discovered in this article. 

In this table, we highlight how psoriasis treatments have evolved over the past four decades. 

New psoriasis treatments are making their way to market. This supplement and the corresponding August issue take a broad look at the evolving understanding of the pathogenesis of psoriasis, the expanding treatment armamentarium, co-morbidity considerations, and financial considerations of new technologies. 

Psoriasis patients face a long list of comorbidities, increased medical costs and increased mortality. Experts agree that the burden of psoriasis is heavy - what can dermatologists do to offer relief?

Psoriasis does not appear to impact fertility, but there are conflicting data on whether psoriasis itself affects the risk of pregnancy complications in women of childbearing age. This expert weighs in on the subject.

About one-third of patients with psoriasis are children or adolescents. Still, little research exists on treating this patient population. New disease management guidelines and emerging studies seek to fill the gap.

Treatment recommendations for psoriasis patients with specific comorbidities.

Based on current data, biosimilars are therapeutically equivalent to their progenitors, says these experts.

“The landscape of biologics and biosimilars is changing rapidly, and for the better,” says Mark Lebwohl, M.D. Biologics have given patients the possibility of complete psoriasis clearance and control of their psoriatic arthritis (PsA), which were not options 20 years ago, adds Alice Gottlieb, M.D., Ph.D.

With the high incidence of psoriasis and psoriatic arthritis among patients who are obese, it’s important for dermatologists to address weight and weight management. But, having that conversation is not always easy. Dr. Soltani-Arabshahi offers tips to help you talk to your psoriasis patients about their weight.

Data shows obesity is prevalent among patients with psoriasis and psoriatic arthritis, but the exact role weight plays in contributing to psoriatic disease and its severity is still unknown. At a minimum, industry experts agree that addressing obesity can be vital in treating psoriatic disease.

Patients often don’t talk about the impact of genital psoriasis because of the stigmatization, feeling shy or fear of judgement. It's up to dermatologists to proactively ask patients about their symptoms, urges a recent review.

Test your knowledge by answering these five questions about different psoriasis cases.

Ortho Dermatologics announced that halobetasol propionate and tazarotene lotion, 0.01%/0.045% (Duobrii, Ortho Dermatologics) is now commercially available to healthcare providers, according to a press release issued June 25.

A recent study found that Psoriasis Epidemiology Screening Tool (PEST) may help dermatologists identify which patients need a rheumatology referral. 

A recent study explored why black individuals with psoriasis are disproportionately under treated. Authors compared differences in the perceptions and understanding of psoriasis therapies in both black and Caucasian patients. Here’s what they found.

Young African American patients with psoriasis are at a higher risk of atherosclerotic cardiovascular disease (ASCVD) and traditional cardiovascular risk factors than white patients with psoriasis of the same age group, says a recent study. 

In psoriasis, many therapies offer roughly the same level of care, but that doesn’t mean any patient will respond well to any therapy. According to Mark Lebwohl, M.D., physicians should consider each treatment option in light of a patient's specific comorbidities. 

Why do biologics lose efficacy over time? This physician discusses factors dermatologists should consider when they see this issue in their patients.

Continued psoriasis research has led to a translational revolution in inflammatory skin diseases. As a result, there are now a number of safer and more effective medications that can address a growing list of common immune-mediated skin diseases, such as atopic dermatitis, alopecia areata, vitiligo, hidradenitis suppurativa, acne, and rosacea.

More and more adults with psoriasis are using alternative remedies in place of traditional allopathic treatments, says a recent survey. One expert believes it’s due to undertreatment of the condition.

A recent study aimed to explore whether patients suffering from psoriasis carry serious medical morbidity, including cancer, that is not detected through history, physical exam and laboratory studies. 

According to a recent study, patients with psoriatic arthritis may be at a greater risk for adult hearing loss than individuals without psoriatic arthritis.

Unlike prior generations of dermatologic drugs, Janus kinase (JAK) inhibitors show potential for treating numerous dermatologic indications. Brett King, M.D., Ph.D. explored what this class of drug has to offer in his presentation during AAD earlier this month.

Researchers found a significant inverse correlation between ustekinumab levels and PASI scores at week 52, suggesting that drug levels are associated with the change in the treatment response. Measuring ustekinumab levels can have major clinical implications.

Guidelines suggest that providing a small test dose of methotrexate to patients followed by laboratory evaluation can minimize the risk of serious adverse events associated with methotrexate. This small retrospective study examined whether methotrexate requires a test dose.

Chief executive officer of Can-Fite Biopharmaceuticals, Pnina Fishman, Ph.D. discovered why cancer and inflammation can go everywhere in the body, except muscle tissue. Using this knowledge, Can-Fite has developed a promising psoriasis drug, piclidenoson, which is currently in phase 3 clinical trials.