
Opinion|Videos|March 21, 2025
The Role of IL-17 in Psoriasis Pathogenesis
Panelists discuss how IL-17 is a key pro-inflammatory cytokine in plaque psoriasis pathogenesis. It stimulates keratinocyte proliferation, promotes neutrophil recruitment, induces antimicrobial peptides, and up-regulates other inflammatory mediators, creating a self-perpetuating inflammatory cascade in lesional skin.
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- What is the role of IL-17 in the pathogenesis of plaque psoriasis, and how does it contribute to inflammation?
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