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A Closer Look at IL-17 Inhibitors in Psoriasis : Episode 3

Opinion

Video

March 28, 2025

Clinical Attributes of IL-17 Inhibitors in Psoriasis

Author(s):

Christopher G. Bunick, MD, PhD,James Song, MD, FAAD

Panelists discuss how IL-17 inhibitors are biologics that target the inflammatory cytokine IL-17 pathway. They demonstrate rapid onset of action, with measurable improvement in most patients within 2 to 4 weeks and peak efficacy by 12 to 16 weeks. They achieve high rates of skin clearance in psoriasis patients and maintain efficacy with long-term use.

EP: 1.The Role of IL-17 in Psoriasis Pathogenesis

EP: 2.Mechanism of Action Differences Among IL-17 Inhibitors

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EP: 3.Clinical Attributes of IL-17 Inhibitors in Psoriasis

EP: 4.IL-17 Inhibitor Treatment Impact on Quality of Life in Psoriasis and Psoriatic Arthritis

EP: 5.Selecting and Dosing IL-17 Inhibitors in Psoriasis

EP: 6.Safety Considerations for IL-17 Inhibitors

EP: 7.Hepatic Safety of IL-17 Inhibitors in Patients With Psoriasis

EP: 8.Long-Term Efficacy and Safety of IL-17 Inhibitors in Psoriasis

EP: 9.Utility of Head-to-Head Studies in Psoriasis Management

EP: 10.Future Directions for IL-17 Inhibitors in Psoriasis and Psoriatic Arthritis Care

Video content above is prompted by the following:

What are some of the clinical attributes of IL-17 inhibitors? How quickly do they work in their onset of action, and how do they impact skin clearance?

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