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Most of the significant recent advances in acne treatment involve changes in vehicle formulation that may improve medications' tolerability, efficacy or both, a leading clinician and researcher says. For treating tough acne cases, another expert adds, dermatologists must use simpler, more patient-friendly regimens.

St. Charles, Ill. - Dermatologist Rany Jazayerli, M.D., says he knew he’d hit the big time when he stumbled upon his own profile on the online encyclopedia Wikipedia.

The concept of nanotechnology, which relies on nano-sized synthetic materials to provide the functionality of automated machines, is nothing new. However, the science of small has moved from electronics into the biological realm. Balancing the benefits and risks of nanotechnology with respect to patient treatment is essential, an expert says.

The orthodox use of strong sunscreens is largely effective in blocking harmful ultraviolet (UV) rays. However, this protective measure is not 100 percent successful. Recent research finds that the once-a-day application of a novel topical serum containing antioxidants not only helps protect the skin from harmful UV rays, it also improves the visible signs of photodamage.

Preliminary, yet promising, outcomes in two patients suggests dual therapy involving limited surgical excision followed by topical application of imiquimod 5 percent cream (Aldara, Graceway) may be an option to consider for treating invasive malignant melanoma surrounded by lentigo maligna (LM) in patients who refuse or are not good candidates for more extensive surgery, according to researchers from the department of dermatology, Saint Louis University School of Medicine, St. Louis.

As attorneys and consultants to thousands of physicians across the country, we are constantly astounded by the attitudes of physicians regarding the sale of their medical practices. Most often, today, we hear the complaint that doctors do not feel they can sell a practice for any significant value. They generally do not feel the practice is "worth anything," especially if they do not have younger partners to buy them out.

A few months ago, I wrote an editorial for Dermatology Times on the subject of Mohs micrographic surgery and its potential abuses. I noted that while the procedure is very beneficial, it is sometimes overused for questionable indications.

Even Mohs surgeons with ample experience in detecting basal cell and squamous cell carcinomas can have difficulty detecting malignant melanocytes in frozen sections, making many apprehensive about using Mohs surgery for lentigo maligna. But proponents of the technique say the fast results and reduced rate of recurrence make Mohs well worth the effort.

As the Food and Drug Administration (FDA) reviews the safety of therapeutic and cosmetic botulinum toxin injections, dermatologists say adding warnings to Botox Cosmetic (botulinum toxin A, Allergan) would be unwarranted.