
Opinion|Videos|March 21, 2025
Limitations and Challenges in Skin Cancer Staging Systems
Author(s)David Cotter, MD, PhD
An expert discusses the patient demographics and clinical features used in traditional staging and risk classification of melanoma and squamous cell carcinoma (SCC), examining how staging systems from organizations like the American Joint Committee on Cancer (AJCC) and National Comprehensive Cancer Network (NCCN) align in risk classification, the challenges of relying solely on clinical features for prognosis, and the importance of accurate risk staging in guiding treatment decisions for these cancers.
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Video content above is prompted by the following:
- Discuss the patient demographics and clinical features that are included in traditional staging and risk classification of melanoma and SCC.
- Do the different staging systems, such as ones used by AJCC and NCCN, generally agree with regard to risk classification? Discuss some of the challenges with basing prognosis strictly on clinical features.
- What is the importance of accurate risk staging? How do treatment guidelines for melanoma and SCC differ based on the patient’s risk profile?
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