Skin Cancer

As dermatologists become increasingly aware of comorbidities associated with psoriasis, questions of associated malignancy risk remain. Dr. Megan Noe emphasizes the need for skin cancer checks.

In this article, we review the American Academy of Dermatology treatment guidelines for cutaneous squamous cell carcinoma.

Solid organ transplant recipients experience an average of two cutaneous squamous cell carcinomas following their transplant.

People who use indoor tanners may be putting themselves at greater risk for skin cancer because they use low SPF sunscreen.

Combination that extends survival in BRAF-mutant metastatic melanoma gains FDA approval.

Two to three months of neoadjuvant topical imiquimod, 5%, cream prior to conservatively staged excisions for lentigo maligna (LM) is associated with a low rate of recurrence.

Chance of metastasis for cutaneous squamous cell carcinomas of vermillion lip is five times greater than on the cutaneous lip, study shows.

Monitoring changes in patients with melanoma can be tricky. Some changes present slowly and in tiny ways. Using imaging technologies to track these changes can help achieve an accurate diagnosis.

Dermatofibrosarcoma protuberans (DFSP), dermatofibromas, keloids and hypertrophic scars are four separate conditions requiring assessment, but only one requires a biopsy.

In this review article, Kaivon Sobhani, B.S., and, Eve Lowenstein, M.D., Ph.D., examine fibrotic skin lesions, including the cutaneous tumor dermatofibrosarcoma protuberan (DFSP).

Nearly half of patients at an outpatient primary care clinic elected to learn about genomic testing to assess their risk of melanoma.

The cost of skin cancer treatments continue to increase in the United States where a large proportion of expenditures stem from the cost of systemic agents for melanoma.

Some melanoma patients prefer fewer follow-up visits, but only if self-skin examinations were utilized at home or teledermatology implemented for a quick assessment.

Changing the schedule of targeted therapies has been shown to improve the response rate in a mouse model of melanoma.

Pediatric melanomas are often misdiagnosed by physicians. Adolescents have a more aggressive disease course than children and are treated with adult protocols leading to chronic morbidity.

The combination of encorafenib plus binimetinib significantly improved overall survival versus vemurafenib in patients with BRAF-mutant melanoma, updated results of the randomized, phase three COLUMBUS trial show.

Researchers reporting at the American Society of Clinical Oncology annual meeting on June 4 presented a study in which they compared the seventh and eighth editions of the American Joint Committee on Cancer melanoma staging systems. The eighth edition differentiates melanoma survival slightly worse than the previous edition.

Pembrolizumab has antitumor activity that is durable long after treatment is stopped in patients with advanced melanoma, researchers reported at the 2018 annual meeting of the American Society of Clinical Oncology (ASCO) on June 4.

In a comparison of the performance between physician assistants and dermatologists, physician assistants may have lower diagnostic accuracy for melanoma than dermatologists, suggests a study published in JAMA Dermatology. The AAPA and SDPA question the use of the NNB ratio to determine diagnostic accuracy.

Studies have shown that melanoma incidence rates among non-Hispanic whites have been rising in recent years, which is true ― to a degree, according to a research letter published in March in JAMA Dermatology. The rates are indeed rising for those younger than 15 years old and older than 45 years old. However, the analysis highlights a big dip in melanoma cases for those between 15-44 years.

 La Roche-Posay is developing a nail art version of My UV Patch with clinical trials to start this year.

Immune system modulators are changing the ways in which dermatologists treat inflammatory skin diseases. But how best to use these medications and for which skin diseases isn’t always clear.

 Biomedical tattoo may permit early diagnosis of diseases associated with hypercalcemia, preliminary study shows.