Skin Cancer

Imiquimod shows promise for treating cases of melanoma in situ that aren’t amenable to surgery, and for other off-label indications such as metastatic melanoma, says M. Shane Chapman, M.D.

The decision to perform a sentinel lymph node biopsy (SLNB) in patients with melanoma requires considering many factors, including the patient’s input, says Clara Curiel-Lewandrowski, M.D.

High-tech imaging modalities are helpful in detecting metastatic neural spread of tumors, a process known as perineural spread (PNS), and thus can be instrumental in better managing the patient, says Barton Lane, M.D.

Despite the number of currently available options for the treatment of actinic keratoses (AKs), dermatologists are still challenged by the occasional patient with widespread lesions refractory to multiple modalities.