Vapocoolant spray pretreatment eases pain

Washington D.C. - Cryoanesthesia using the refrigerant spray dichlorotetrafluoroethane (Freon 114; Frigiderm) safely and effectively reduces the pain of botulinum toxin type A (Botox) injections for palmar hyperhidrosis but does not interfere with the efficacy of that treatment for decreasing sweating, said Leslie S. Baumann, M.D., at the annual meeting of the American Academy of Dermatology here.