Anthony Rossi MD, FAAD, FACMS, Discusses Science, Simplicity, and the Skin

In the second part of his interview with Dermatology Times, Anthony Rossi, MD, FAAD, FACMS, a double board-certified dermatologist and dermatologic surgeon at Memorial Sloan Kettering, shared insights into the clinical research, product development, and vision behind his skin care brand, Dr. Rossi DERM MD.

The foundation of the line lies in the modulation of the TRPV1 receptor, which plays a critical role in skin sensitivity and inflammation. Clinical trials, published in the Journal of Drugs in Dermatology, showed statistically significant improvements in key skin concerns—including redness, wrinkling, under-eye darkness, and hydration—within just 4 weeks.¹ These outcomes were validated using VISIA Canfield technology and backed by both objective data and positive patient-reported outcomes.

Rossi emphasized the unique challenges of founding a skin care brand as a practicing dermatologist. Unlike many consultant-led lines, he was directly involved from concept to formulation, with a focus on dermatologic integrity. Products were developed in Seoul, Korea, to leverage advanced formulation techniques while eliminating commonly sensitizing ingredients. The result is what Rossi describes as “a marriage of this really hardcore dermatologic science with this K-beauty aesthetic that has created really unique formulations.”

A new standout in the line is the Day Formula, a patent-pending mineral-based SPF 30/PA+++ “smart sunscreen” that also functions as a moisturizer. Infused with titanium dioxide, niacinamide, diamonds, and triglycerides, it offers broad-spectrum protection with anti-inflammatory and barrier-supportive benefits. The product has already earned accolades from CNN Underscored and the Boston Derm Advocate.

Rossi’s ethos centers on simplicity and performance, offering only 6 essential products, including a gentle cleanser, lactic acid essence, peptide-rich serum, overnight moisturizer, eye cream, and the Day Formula. The line is widely used post-procedurally by fellow dermatologists, underscoring its efficacy and tolerability for compromised or inflamed skin.

“As a dermatologist, you really have to stand for integrity and science, and that's what I'm trying to bring to this brand,” Rossi said. ‘This is not just about repping the next novel or cute idea. This is really an ethos about keeping it simple.”

Rossi concluded with a reminder that amidst skin care trends and marketing noise, dermatologist-led, science-driven care remains critical. With Dr. Rossi DERM MD, he aims to provide evidence-based, thoughtfully formulated products that serve both clinical and everyday needs.

“I'm really proud to know that other dermatologists are actually picking up the line and selling it in their office, because that's the greatest brand approval for me,” he concluded.

To learn more about adding these products to your practice, visit the Dr. Rossi DERM MD website.

Reference

1. Shah R, Kaul N, Tan I, Rossi A. Clinical Utility of TRPV1 Modulation for Skincare Sensitivity. J Drugs Dermatol. 2025;24(4):366-370. doi:10.36849/JDD.8680